Injection site reactions—such as redness, itching, bruising, swelling, and pain—can affect up to 1 in 10 users of GLP-1 medications like Mounjaro and Wegovy. These symptoms often improve over time as your body adjusts, but here are some helpful strategies to manage them:
1. Consider Antihistamines
- Non-drowsy antihistamines like cetirizine can help reduce itching and redness.
- Topical treatments: Local antihistamine or mild steroid creams applied directly to the area can offer fast relief. Ask your local pharmacist for a suitable recommendation.
2. Rotate Injection Sites
- Change your injection location regularly—for example, alternate between your abdomen and thighs—to reduce skin irritation in any one spot.
3. Practice Gentle Care
- Avoid rubbing or scratching the area, as this can worsen symptoms.
- Cool compresses: Gently applying a cool, damp cloth to the site can help soothe itching and reduce swelling.
🚨 When to Seek Help
Seek urgent care by contacting NHS 111 or your GP if:
- You experience a worsening or spreading rash, or if redness and swelling become increasingly painful or persistent.
- You develop severe pain or additional symptoms like fever or difficulty breathing—this may indicate an allergic or more serious reaction.
📩 Let Us Know
Please also notify our Lotus Weight Loss clinical team if you experience any moderate to severe injection site reactions.
At Lotus Weight Loss, we’re here to support you at every step of your journey. If you’re concerned about injection site reactions—or any other side effects—please get in touch with our clinical team or your NHS GP for personalised advice.